Odds ratios (ORs) and 95% confidence intervals (95%CIs) of colorectal cancer according to quartiles of total choline and betaine intake stratified by selected variables.

a Intakes of folate were adjusted for the daily energy intake using the residual method.b Odds ratio was adjusted for age (continuous), sex (men/women), residence (urban/rural), marital status (married/other), education (primary school or blow/secondary school/high school/college or above), income level (8,001), occupation (white collar worker/blue collar worker/farmer or other), family history of cancer (yes/no), smoking status (current/never or past), passive smoking (yes/no), alcohol drinking (yes/no), degree of physical activity (less active/moderate active/more active), and BMI (continuous).c Odds ratio was adjusted for the various above confounders except sex and folate intake (continuous).d. Odds ratio was adjusted for the various above confounders and menopausal status in women.Odds ratios (ORs) and 95% confidence intervals (95%CIs) of colorectal cancer according to quartiles of total choline and betaine intake stratified by selected variables.a. 采用残差法对叶酸摄入量进行每日能量摄入校正。 b. 比值比（Odds Ratio, OR）校正因素包括：年龄（连续型变量）、性别（男/女）、居住地（城镇/乡村）、婚姻状况（已婚/其他）、受教育程度（小学及以下/中学/高中/大专及以上）、收入水平（8001）、职业（白领/蓝领/农民及其他）、癌症家族史（是/否）、吸烟状态（当前吸烟/从不吸烟或已戒烟）、被动吸烟（是/否）、饮酒（是/否）、体力活动水平（低活动量/中等活动量/高活动量）以及体质量指数（Body Mass Index, BMI，连续型变量）。 c. 比值比校正上述各类混杂因素，但除外性别与叶酸摄入量（连续型变量）。 d. 比值比校正上述各类混杂因素及女性绝经状态。 按选定变量分层后，不同总胆碱与甜菜碱摄入量四分位数对应的结直肠癌比值比（OR）及95%置信区间（95%CI）。