Neuropsychological profile of CBS patients according to PiB status.

aPiB-positive v PiB-negative, PbPiB-negative v Controls, PcPiB-positive v Controls, PAlthough both CBS groups demonstrated cognitive impairment compared to controls, PiB-positive CBS patients demonstrated more cognitive impairment than PiB-negative cases, with significant visuospatial impairment, and executive dysfunction. In addition, there was a trend for impaired memory in the PiB-positive group. Note: some tasks that required manipulation of a pencil, such as the Rey-Osterrieth Complex Figure and Trails, had to be abandoned in some CBS patients due to severe apraxia of the dominant limb.a) 匹兹堡化合物B（Pittsburgh Compound B，简称PiB）阳性组与PiB阴性组、b) PiB阴性组与对照组、c) PiB阳性组与对照组的对比。尽管两组皮质基底节综合征（Corticobasal Syndrome，简称CBS）患者相较于对照组均存在认知损害，但PiB阳性的CBS患者的认知损害程度较PiB阴性患者更为显著，同时伴随明显的视空间障碍与执行功能障碍。此外，PiB阳性组存在记忆损害的趋势。备注：部分需要使用铅笔操作的任务，如雷-奥斯特里赫复杂图形测验（Rey-Osterrieth Complex Figure）与连线测验（Trails），因部分CBS患者存在严重的优势肢体失用症而不得不中止实施。