Data supporting: Imatinib Detection by Memristive Biosensors for Therapeutic Drug Monitoring

This dataset contains the experimental data supporting the publication: Imatinib Detection by Memristive Biosensors for Therapeutic Drug Monitoring. The study presents a silicon nanowire (SiNW)-based memristive biosensor functionalized with a ssDNA aptamer for the electrical detection of imatinib in buffer solutions and human plasma. The dataset includes electrical characterization data (I–V measurements), voltage gap (Vg) extraction data, calibration curves in buffer and plasma, interference experiments with HSA and AGP proteins, as well as representative SEM and fluorescence microscopy images. Devices consist of quasi-1D silicon nanowires forming back-to-back Schottky junctions. Electrical measurements were performed using a laboratory source measurement unit connected to a probe station. Files are organized according to the corresponding figure numbers in the manuscript. Each figure folder contains the numerical data used to generate the published figures, along with the associated figure image. The numerical files correspond to instrument-generated measurement outputs. In cases where raw instrument files were not retained, the provided data represent the validated experimental outputs used for figure generation.本数据集包含支撑下述已发表论文的实验数据：《基于忆阻生物传感器检测伊马替尼用于治疗药物监测》。 本研究提出了一种基于硅纳米线（silicon nanowire, SiNW）的忆阻生物传感器，该传感器经单链DNA（single-stranded DNA, ssDNA）适配体修饰后，可在缓冲液与人体血浆中实现伊马替尼的电学检测。 本数据集涵盖电学表征数据（电流-电压（I-V）测量数据）、电压间隙（voltage gap, Vg）提取数据、缓冲液与血浆中的校准曲线数据、针对人血清白蛋白（human serum albumin, HSA）与α1-酸性糖蛋白（alpha-1 acid glycoprotein, AGP）的干扰实验数据，以及典型的扫描电子显微镜（scanning electron microscope, SEM）与荧光显微镜图像。 该器件由构成背靠背肖特基结的准一维硅纳米线组成。 电学测量采用连接至探针台的实验室级源测量单元完成。 数据集文件按照论文手稿中的对应图号进行组织。每个图文件夹均包含用于生成已发表图表的数值数据，以及配套的图表图像文件。 数值文件对应仪器生成的测量输出结果。若原始仪器测量文件未留存，则本数据集提供的数据为经验证的、用于生成图表的实验输出结果。