Additional file 2 of Systematic evaluation of B-cell clonal family inference approaches
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Additional file 2. Evaluated approaches for clonal famility reconstruction. BcR repertoire datasets used to evaluate clonal familty reconstruction approaches. Results of outcome measures for all approaches applied to all datasets. Performance of 10 approaches applied to two samples from three simulated datasets. Heavy chain (HC) and Light chains (LC) in single cell datasets D4 (Claireaux et al, 2022) and D5 (DeKosky et al., 2013). Concordance analysis of HC-based clonal families. Shared Clonal Families. Dominant shared Clonal Families for D9.2 (single RA patient).
附加文件2。用于克隆家族重建的评估方法。用于评估克隆家族重建方法的B细胞受体(BcR)库数据集。针对所有数据集应用全部方法所得结局指标的结果。针对3个模拟数据集的2份样本所应用的10种方法的性能表现。单细胞数据集D4(Claireaux等人,2022年)与D5(DeKosky等人,2013年)中的重链(HC)与轻链(LC)。基于重链的克隆家族的一致性分析。共享克隆家族。D9.2(单例类风湿关节炎(RA)患者)的优势共享克隆家族。
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figshare
创建时间:
2024-08-14



