Primary neuron model of Huntington's Disease. 2 treatment groups: A) Infected 4 weeks prior with TRE-Htt-N853-18Q-expressing recombinant lentivirus, B) Infected 4 weeks prior with TRE-Htt-N853-82Q-exp
Huntington's disease (HD) is associated with dysfunction of the blood-brain barrier, including brain microvasscular endothelial cells (BMECs). We report changes in gene expression of induced pluripote
Selected autophagy markers were analyzed by qRT-PCR in hypothalamic tissue from mice injected with rAAV5-htt853-79Q or rAAV5-htt853-18Q and uninjected controls, 8 weeks post injection (n = 7/group). T
