HLA-DQ8 Immunopeptidomics, Type 1 Diabetes

NIAID Data Ecosystem2026-03-12 收录

免疫肽组学

自身免疫糖尿病

数据链接：

https://www.omicsdi.org/dataset/pride/PXD019466 数据链接链接失效反馈

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In this project we will investigate the peptides present by HLA-DQ8. We will identify linear, spliced and PTM peptides from one cell line.

创建时间：

2021-07-07

A large fraction of HLA class I ligands are proteasome-generated spliced peptides.

免疫肽组学

HLA配体鉴定

The HLA-I-eluted immunopeptidome of the GR lymphoblastoid cell line (GR-LCL) was analyzed by a two-dimensional (2D) peptide prefractionation strategy followed by a hybrid peptide fragmentation method

ImmuneData50

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

免疫肽组学

抗原表位预测

The epitope was eluted from B721.221 cells tranfected with HLA-A29:02.

ImmuneData30

Transcription profiling of mouse autoimmune and diabetic NOF animals reveals the curative and beta cell regenerative effects of alpha1 antitrypsin treatment

自身免疫糖尿病

β细胞再生研究

Transcription profiling of mouse autoimmune and diabetic NOF animals reveals the curative and beta cell regenerative effects of alpha1 antitrypsin treatment

ChEBI2009-01-14 更新20

Core sequence of a subset of abundant self-peptides isolated from both T cells and B cells (donor 1).

免疫肽组学

MHC-II抗原呈递

The core sequence represents the largest consensus peptide sequence identified for total nested protein fragments across all samples for a single donor. The total number of peptides identified for don

Figshare2015-12-02 更新50

Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands.

免疫肽组学

HLA配体鉴定

The epitope was eluted from human B-lymphoblastoid cell lines expressing full-length or truncated HLA A*02:01 gene such that they express membrane-bound and secreted HLA A*02:01, or JETHOM cells.

ImmuneData30

HLA-DQ8 Immunopeptidomics, Type 1 Diabetes

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