Invasive breast carcinoma of no special type - Female, 63 - Tissue image [6270730022329601]

This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 63Clinical description: Tumor of right breast. 15 x 13 mm hypoechoic tumor on ultrasound. Suspicion of breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast carcinoma (NOS) NHG 3 (3+3+2: 9 mitoses/10 HPF) (e-cadherin+) and ductal carcinoma in situ (DCIS) NG3, LVI+. ER-, PR-, HER2-, Ki-67 80%.Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Upper-outer quadrant of breastType of staining: positive/IHCStaining: Not applicableAntibody: E-CadherinTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存储于ZMDL-GUMED数据库的乳腺组织样本组织病理学图像。该样本图像通过Pannoramic 250 3DHistech切片扫描仪（放大倍率20×）采集，并以DICOM格式存储。

患者及诊断详细信息如下：
患者：
年龄：63岁
临床描述：右侧乳腺肿瘤，超声检查可见15×13mm低回声肿物，疑似乳腺癌。
性别：女性
诊断分类：ICD-O_3.2分类
分类编码：导管及小叶上皮肿瘤（DUCTAL AND LOBULAR NEOPLASMS）
确诊诊断：非特殊类型浸润性乳腺癌
组织病理学检查结果：非特殊类型浸润性乳腺癌（NOS），诺丁汉组织学分级（NHG）3级（评分3+3+2：每10个高倍视野见9个核分裂象），E-钙粘蛋白（E-cadherin）阳性；同时伴NG3级导管原位癌（Ductal Carcinoma In Situ, DCIS），脉管浸润阳性（LVI+）。免疫组化标志物结果：ER阴性、PR阴性、HER2阴性，Ki-67增殖指数为80%。

样本详情：
样本材质：福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）样本
采集方式：手术标本
取材部位：乳腺外上象限
所属器官：乳腺
组织类型：乳腺外上象限
染色类型：免疫组化阳性染色（positive/IHC）
染色方案：不适用
抗体靶点：E-钙粘蛋白（E-Cadherin）
成像设备：Pannoramic 250 3DHistech
镜头放大倍数：20×
来源机构：格但斯克医科大学（Medical University Gdańsk）