Averaged rmsds (Å) of the 7TM bundle pairs in the inactive state for class A GPCRs of known structure.

Amino acid sequence identity (%) is also shown in parenthesis. The range of each helix contained in a 200 residue 7TM bundle with Ballesteros & Weinstein numbering is as follows: helix I, 1.35–1.59 (25 a.a.); helix II, 2.38–2.67 (30 a.a.); helix III, 3.22–3.55 (34 a.a.); helix IV, 4.39–4.63 (25 a.a.); helix V, 5.36–5.65 (30 a.a.); helix VI, 6.29–6.60 (32 a.a.); helix VII, 7.32–7.55 (24 a.a.). brh and srh stand for bovine rhodopsin and squid rhodopsin, respectively.