Date set of the study.

We evaluated the association between T. gondii seropositivity and violent behavior in a sample of inmates in Durango, Mexico. Through a cross-sectional study design, we studied 128 inmates (mean age: 35.89 ± 10.51; range: 19–65 years). Sera of participants were analyzed for anti-T. gondii IgG antibodies using a commercially available enzyme-linked immunosorbent assay. Violence was assessed by 1) the Historical, Clinical and Risk Management-20 (HCR-20) tool; 2) the type of the crime for which inmates were convicted; and 3) the Buss-Perry Aggression Questionnaire (AGQ). Of the 128 inmates, 17 (13.3%) had high risk of violence by the HCR-20 criteria, 72 (56.3%) were considered violent by the type of the crime committed, and 59 (46.1%) were considered violent by the AGQ. Depending on the evaluation method of violence, the seroprevalence of T. gondii infection in violent inmates varied from 0% to 6.9%. No statistically significant difference in anti-T. gondii IgG seroprevalence between violent and non-violent inmates was found (for instance by AGQ, OR: 1.17; 95% CI: 0.22–6.07; P = 1.00). Mean scores of the AGQ in T. gondii seropositive inmates (73.67 ± 29.09; 95% CI: 50.00–99.31) were similar to those (79.84 ± 25.00; 95% CI: 75.46–84.27) found in T. gondii seronegative inmates (P = 0.55). Mean scores of anger, psychical aggression, verbal aggression, and hostility in T. gondii seropositive inmates were similar to those found in T. gondii seronegative inmates. Results of this study suggest that infection with T. gondii is not associated with violence in inmates in Durango, Mexico. Further studies with larger sample sizes and in several correctional facilities to determine the association between T. gondii infection and violence in inmates are needed.本研究针对墨西哥杜兰戈州的服刑人员样本，评估了刚地弓形虫（Toxoplasma gondii）血清阳性与暴力行为之间的关联。本研究采用横断面研究设计，共纳入128名服刑人员（平均年龄35.89±10.51岁，年龄范围19~65岁）。采用商品化酶联免疫吸附试验（enzyme-linked immunosorbent assay, ELISA）检测受试者血清中的抗刚地弓形虫IgG抗体。暴力行为评估采用以下三种方式：1）历史、临床和风险评估量表-20（Historical, Clinical and Risk Management-20, HCR-20）；2）服刑人员所定罪的犯罪类型；3）巴斯-佩里攻击问卷（Buss-Perry Aggression Questionnaire, AGQ）。在128名服刑人员中，依据HCR-20评估标准，有17人（13.3%）存在高暴力风险；依据所犯罪行类型，72人（56.3%）被归类为暴力型服刑人员；依据AGQ评分，59人（46.1%）被归类为暴力型服刑人员。依据不同的暴力行为评估方法，暴力型服刑人员的刚地弓形虫感染血清阳性率在0%~6.9%之间波动。未发现暴力型与非暴力型服刑人员之间的抗刚地弓形虫IgG血清阳性率存在统计学差异（例如以AGQ评估为例，优势比OR=1.17；95%置信区间CI：0.22~6.07；P=1.00）。刚地弓形虫血清阳性服刑人员的AGQ平均得分（73.67±29.09；95%CI：50.00~99.31）与血清阴性服刑人员的AGQ平均得分（79.84±25.00；95%CI：75.46~84.27）无显著差异（P=0.55）。刚地弓形虫血清阳性服刑人员的愤怒、躯体攻击、言语攻击及敌意维度平均得分，与血清阴性服刑人员相比均无显著差异。本研究结果表明，墨西哥杜兰戈州服刑人员的刚地弓形虫感染与暴力行为无关联。未来需开展更大样本量、多监禁机构环境的研究，以明确服刑人员刚地弓形虫感染与暴力行为之间的关联。