Row data for the experiment: "Clinical, psychosocial and demographic factors affect decisions in SLE people".

These datasets correspond to the article titled: “Clinical, psychosocial and demographic factors affect decisions in SLE people”, which can be found at https://www.medrxiv.org/content/10.1101/2024.03.25.24304643v1.full.pdf Analysis scripts, and an explanation of variables, can be found at: https://github.com/NeuroGenomicsMX/Factors_affecting_decisions_in_SLE Abstract Neurological and psychiatric manifestations affect most lupus individuals and include depression, anxiety, mood disorders, and cognitive dysfunction. Although there is evidence supporting suboptimal decision-making in lupus and its association with glucocorticoids consumption, it is not clear what variables impact such decisions. The aim of this study is to explore how social, clinical, psychological, and demographic factors impact social and temporal decision-making in people with lupus. Through a within-subjects experimental-design, our participants responded to social, clinical, psychological, and demographic electronic questionnaires. Then, they participated in two behavioral economics experiments: the third-party dictator game, and the delay discounting task. Our results show that hostility, and age are essential predictors of social decisions, whereas obsessive-compulsiveness and anxiety better predict temporal decisions. These variables behave as expected, but anxiety shows unexpected results: most anxious people act patiently and prefer delayed but bigger rewards. Finally, clinical factors are critical decision predictors for social and temporal decisions. When people are in remission, they tend to impose higher punishment on those who violate the social norm, and they also tend to prefer immediate rewards. When taking glucocorticoids, they also prefer immediate rewards, and as the dosage of glucocorticoids intake increases, they tend to impose higher punishment on norm violators. Clinicians, researchers, and practitioners must consider the side effects of glucocorticoids on decision-making.本数据集对应题为《临床、社会心理与人口统计学因素影响系统性红斑狼疮（Systemic Lupus Erythematosus, SLE）患者的决策》的研究论文，可通过https://www.medrxiv.org/content/10.1101/2024.03.25.24304643v1.full.pdf获取全文。 分析脚本及变量说明可在https://github.com/NeuroGenomicsMX/Factors_affecting_decisions_in_SLE查看。 摘要 神经精神症状累及多数系统性红斑狼疮患者，涵盖抑郁、焦虑、心境障碍及认知功能障碍。尽管已有证据表明狼疮患者存在次优决策，且该现象与糖皮质激素摄入存在关联，但目前尚不明确究竟哪些变量会对这类决策产生影响。本研究旨在探索社会、临床、心理及人口统计学因素如何影响狼疮患者的社会决策与时间决策。本研究采用被试内实验设计，让受试者完成涵盖社会、临床、心理及人口统计学信息的电子问卷。随后，受试者参与两项行为经济学实验：第三方独裁者博弈（third-party dictator game）与延迟折扣任务（delay discounting task）。 研究结果显示，敌意特质与年龄是社会决策的关键预测因子，而强迫症状与焦虑则更能有效预测时间决策。上述变量的预测效应均符合预期，但焦虑维度的结果却出乎意料：多数焦虑个体表现出更具耐心的决策倾向，更偏好延迟但收益更高的奖励。此外，临床因素对社会决策与时间决策均具有显著预测价值。处于疾病缓解期的患者，会对违反社会规范的行为施加更严厉的惩罚，同时更倾向于选择即时奖励。而服用糖皮质激素的患者同样偏好即时奖励，且随着糖皮质激素摄入剂量的增加，患者对违规者的惩罚力度也会随之提升。临床医师、科研人员及从业者均需重视糖皮质激素对决策功能的副作用。