Additional file 2: of Amplified fragment length polymorphism and whole genome sequencing: a comparison of methods in the investigation of a nosocomial outbreak with vancomycin resistant enterococci

Table S1. All available characteristics of the isolates included in either AFLP, WGS or both analysis methods. NLD = Netherlands, PRT = Portugal, GRC = Greece, DK = Denmark. Phenotypic vancomycin susceptibility testing per typed isolate by VITEK and confirmatory E-test (EUCAST clinical cut-off > 4 mg/L). *The same isolate grown on another plate had an e-test MIC of 8 mg/L. **E-test not done. Same isolate grown on another plate had an e-test MIC of 16 mg/L. Table S2. Core-SNP matrix indicating core-SNP differences between each isolate. Boxed are the core-SNP differences between the Index isolate S01 and all other isolates. (XLSX 23 kb)

附表S1：纳入AFLP（扩增片段长度多态性，Amplified Fragment Length Polymorphism）、WGS（全基因组测序，Whole Genome Sequencing）分析或同时采用两种分析方法的所有菌株的全部特征。其中NLD代表荷兰（Netherlands），PRT代表葡萄牙（Portugal），GRC代表希腊（Greece），DK代表丹麦（Denmark）。所有经分型的菌株均通过VITEK系统开展表型万古霉素敏感性检测，并辅以E-test进行确认，检测折点遵循EUCAST标准：＞4 mg/L。* 同一菌株于另一平板培养后，经E-test测得的最低抑菌浓度（Minimum Inhibitory Concentration, MIC）为8 mg/L。** 未进行E-test检测，同一菌株于另一平板培养后，经E-test测得的最低抑菌浓度（MIC）为16 mg/L。

附表S2：用于展示各菌株间核心单核苷酸多态性（core-SNP）差异的核心-SNP矩阵。框选区域为索引菌株S01与其余所有菌株之间的核心-SNP差异。（XLSX格式，大小23 kb）