MolProbity Structural Validation Reports — Wild-Type, L70H, and R130Q PTEN Models

Full MolProbity all-atom structural validation reports for three PTEN protein models — wild-type, L70H mutant, and R130Q mutant — generated in support of the manuscript: "First-in-Class Cross-Species Computational Identification of a Novel Benzimidazole–Phenol Scaffold Targeting Wild-Type and Hotspot Mutant PTEN in Glioblastoma." Published in Journal of Chemical Information and Modeling. Each HTML file contains the complete MolProbity output including Ramachandran analysis, clashscore, rotamer outliers, and Cβ deviation plots for the respective structural model. Keywords: PTEN glioblastoma MolProbity structural validation homology modelling L70H R130Q本数据集包含针对三种PTEN蛋白模型（野生型、L70H突变体与R130Q突变体）的全原子MolProbity（MolProbity）结构验证报告，相关内容为支持发表于《Journal of Chemical Information and Modeling》的论文《First-in-Class Cross-Species Computational Identification of a Novel Benzimidazole–Phenol Scaffold Targeting Wild-Type and Hotspot Mutant PTEN in Glioblastoma》所生成。每份HTML文件均包含对应结构模型的完整MolProbity输出内容，涵盖拉氏构象分析（Ramachandran analysis）、冲突评分（clashscore）、rotamer离群值（rotamer outliers）以及Cβ偏差绘图数据。 关键词： PTEN 胶质母细胞瘤（glioblastoma） MolProbity 结构验证 同源建模（homology modelling） L70H R130Q