Dataset annotating different features of human cell lines in biological and biomedical research

Human cell lines are perhaps the go-to tool for initiating studies in many biological and biomedical research fields. While there are many papers to guide neophytes researchers along the journey, many aspects of cell culture and maintenance remain experiential and require months of training in order to obtain reproducible results. What is perhaps lacking is some foundational understanding of the cell lines used in research. This dataset is a cursory effort in this direction that attempts to summarize the key features of common human cell lines in biological and biomedical research. Features documented include organ of origin, disease model, cell type, and purpose of use. It is hoped that this small dataset will help provide the architecture for researchers interested in biomedical problems to also use a similar concept in building their own database on which more discoveries can be made.

人类细胞系或许是诸多生物学与生物医学研究领域启动研究的首选工具。尽管已有诸多文献可为新手研究者提供研究路径指引，但细胞培养与维持的诸多环节仍依赖经验，且需历经数月培训方能获得可重复的实验结果。当前或许仍欠缺的是对研究中所用细胞系的基础认知。本数据集正是朝着该方向做出的初步尝试，旨在汇总生物医学与生物学研究中常用人类细胞系的关键特征。所记录的特征包括细胞来源器官、疾病模型、细胞类型及用途。本数据集希望能为关注生物医学问题的研究者提供参考框架，使其也可运用类似思路构建自有数据库，进而催生更多科研发现。