Moringa study data

This dataset presents the 21-day old weaned male Sprague-Dawley rats. They were received and terminated in batches. Each batch spent ten weeks of intervention before it was terminated.These rats(n=50) were randomized to six treatment groups (n=8-9) with unlimited access to commercial rat feed. Either plain water (C) or 20% fructose solution (Fr) were provided to drink. 400 mg.kg-1 M. oleifera methanolic leaf extract (Mo) or 100 mg.kg-1 fenofibrate were also administered daily for ten weeks. Growth, circulating metabolites, visceral and epididymal fat pads mass, hepatic lipids and general health markers were assessed.Liver samples were histologically examined using H&E stain. Analysis of the data was done with GraphPad Prism 5.0v for windows (GraphPad Software, Inc. CA), and the data were expressed as mean ± standard deviation and analysed by means of a one-way analysis of variance (ANOVA). Statistical significance was considered at P本数据集的实验对象为21日龄断奶的雄性斯普拉格-道利（Sprague-Dawley）大鼠。实验大鼠按批次接收并分批实施安乐处死，每一批大鼠在接受为期10周的干预措施后被处死。本研究共纳入50只大鼠，随机分为6个处理组（每组n=8~9），所有大鼠均可自由采食商业化大鼠饲料，并分别提供纯水（对照组C）或20%果糖溶液（Fr组）作为饮用水；每日额外给予400 mg·kg⁻¹的辣木（Moringa oleifera）甲醇叶提取物（Mo组）或100 mg·kg⁻¹的非诺贝特灌胃，持续干预10周。实验期间对大鼠的生长状况、循环代谢物水平、内脏及附睾脂肪垫重量、肝脏脂质含量与整体健康标志物进行了检测评估。采用苏木精-伊红（H&E）染色法对肝脏样本开展组织学检查。数据分析采用Windows版GraphPad Prism 5.0软件（GraphPad Software, Inc., 加利福尼亚州）完成，实验数据以平均值±标准差表示，采用单因素方差分析（ANOVA）进行统计学检验。统计学显著性判定阈值设定为P。