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Expected power for an association study from the derived equations and observed averaged power from simulation.

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Figshare2015-12-02 更新2026-04-29 收录
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h2: variance explained by the locus.a: in case-control samples, 50% of the sample are cases, P = 0.5.Exp: Expected power based on NCP derived from equation (1)∼(4).Obs: Averaged power over 10000 replicates of simulation.SE: Empirical standard error over 10000 replicates.

h₂:该位点解释的方差。a:在病例-对照样本中,50%的样本为病例,P=0.5。Exp:基于式(1)~(4)推导所得非中心参数(non-centrality parameter, NCP)计算的期望检验效能。Obs:10000次模拟重复实验的平均检验效能。SE:10000次重复实验的经验标准误。

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2015-12-02
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