Additional file 1: of The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic review

Table S1. The characteristics of the studies included. Table S2. The characteristics of the studies included. Table S3. Pair-wise comparisons between modalities for sensitivity, specificity, PLR, NLR, and AUC. Table S4. The result of meta-regression and subgroup analysis for PCT. Table S5. The result of meta-regression and subgroup analysis for CRP. Table S6. The result of meta-regression and subgroup analysis for presepsin. Table S7. Subgroup analysis of region and detection method for PCT and CRP. Table S8. Subgroup analysis of region and cutoff level for PCT and CRP. Table S9. Subgroup analysis of cutoff level for PCT and CRP. Table S10. Sensitivity analyses of PCT, CRP, PCTâ +â CRP, and presepsin. (ZIP 100 kb)

补充表S1 纳入研究的基本特征。
补充表S2 纳入研究的基本特征。
补充表S3 不同检测方法间针对灵敏度（sensitivity）、特异度（specificity）、阳性似然比（positive likelihood ratio, PLR）、阴性似然比（negative likelihood ratio, NLR）及曲线下面积（area under curve, AUC）的两两比较。
补充表S4 降钙素原（procalcitonin, PCT）的Meta回归与亚组分析结果。
补充表S5 C反应蛋白（C-reactive protein, CRP）的Meta回归与亚组分析结果。
补充表S6 普雷塞平（presepsin）的Meta回归与亚组分析结果。
补充表S7 降钙素原（PCT）与C反应蛋白（CRP）按地区及检测方法开展的亚组分析。
补充表S8 降钙素原（PCT）与C反应蛋白（CRP）按地区及临界值开展的亚组分析。
补充表S9 降钙素原（PCT）与C反应蛋白（CRP）按临界值开展的亚组分析。
补充表S10 降钙素原（PCT）、C反应蛋白（CRP）、PCT联合CRP及普雷塞平（presepsin）的敏感性分析。（压缩包大小：100 KB）