The distances in the open and closed eIF4A states.

The length of whole eIF4A protein (black line), the mass center distance between two domains (magenta line) and the length of the linker (blue line) for (A) the open eIF4A state for the O-eIF4A model and (B) the closed eIF4A state in the ATP+RNA+C-eIF4A model; the α helices and β strands at the N-domain – C-domain interface are labeled and shown in cartoon form with the remaining part of the protein colored in white semi-transparent surface; the ATP and RNA molecules are shown by magenta stick and pink cartoon, respectively, in the closed state.