Mice were given vehicle control, SFN (25 mg/kg), TP (1.0 mg/kg), SFN (25 mg/kg)+TP (1.0 mg/kg) by intraperitoneal injection. Mice were sacrificed under anesthesia 24 h after triptolide treatment. Valu
A problem that has hindered the study of the biological properties of certain DNA adducts, such as those that form at the N7 atoms of purines, is their extreme chemical lability. Conditions are descri
