Adverse Outcomes Associated with Systemic Glucocorticoids: Dose–Time Effects in Real-World Inflammatory Disease Cohorts covering 3.7 million patients

This repository contains additional aggregated results from the study Adverse Outcomes Associated with Systemic Glucocorticoids: Dose–Time Effects in Real-World Inflammatory Disease Cohorts, covering approximately 3.7 million patients. The uploaded materials provide detailed incidence rate ratios for adverse outcomes stratified by underlying inflammatory condition and specific adverse event, differentiated by average daily and cumulative systemic glucocorticoid (SCS) dose exposure. The repository further includes Kaplan–Meier plots illustrating the probability of incident adverse events following initiation of SCS therapy, as well as visualisations of piece-wise exponential additive mixed models (PAMMs) that decompose dose- and time-dependent risk patterns. All data are provided in aggregated, deidentified form for transparency and reproducibility.本数据集仓库收录了一项题为《系统性糖皮质激素相关不良结局：真实世界炎症疾病队列中的剂量-时间效应》的研究的补充汇总结果，该研究覆盖约370万名患者。本次上传的材料提供了按潜在炎症疾病类型与特定不良事件分层的不良结局发病比率详情，且区分了平均每日与累积系统性糖皮质激素（systemic glucocorticoid, SCS）暴露剂量。本仓库还包含卡普兰-迈耶曲线（Kaplan–Meier plots），用于展示启动SCS治疗后新发不良事件的发生概率；同时收录了分段指数加性混合模型（piece-wise exponential additive mixed models, PAMMs）的可视化结果，该模型可拆解剂量与时间依赖性的风险模式。所有数据均以汇总、去标识化的形式提供，以保障研究的透明度与可复现性。