Signature miRNA expression comparison between activated B cells and CLL cells relative to control B cells.

Up and down arrows indicate upregulation or downregulation of specific miRNAs, respectively, when compared to untransformed, control B cells. A parallel line indicates no change when compared to untransformed, control B cells. miR-223, miR-29a, miR-29b and miR-29c are upregulated in response to certain B cell activators and downregulated in response to other B cell activators. miR-26a is unaffected by IgM stimulation, but upregulated in response to other B cell activators.