Investigating the conformational changes of OEA on HIF-3A-ARNT by HDX-MS
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
We used hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investigate the influence of OEA on HIF-3A-ARNT.HDX-MS data indicated that OEA binding stabilized multiple residues within the Gβ and Fα regions of HIF-3A PAS-B domain.It is possible that the stabilized Gβ and Fα function as an “interlayer” to further contact with the AB-loop of ARNT.
创建时间：
2022-05-20
