Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a serine acetyltransferase (CysE) derived peptide

Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a serine acetyltransferase (CysE) derived peptide Descriptor: Cysteine synthase, Serine acetyltransferase (CysE) derived peptide Authors: Pederick, J.L, Vandborg, B.C, Bruning, J.B. Deposit date: 2023-05-07 Release date: 2024-11-13 Last modified: 2025-05-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK). Acs Infect Dis., 11, 2025

本数据集收录了金黄色葡萄球菌（Staphylococcus aureus）NCTC 8325菌株的O-乙酰-L-丝氨酸巯基酶A（O-acetyl-L-serine sulfhydrylase A，CysK）与丝氨酸乙酰转移酶（serine acetyltransferase，CysE）衍生肽结合的晶体结构。
描述：半胱氨酸合酶、丝氨酸乙酰转移酶（CysE）衍生肽
作者：Pederick, J.L.、Vandborg, B.C.、Bruning, J.B.
存档日期：2023-05-07
发布日期：2024-11-13
最后修改日期：2025-05-28
实验方法：X射线衍射（1.5 Å）
引用文献：《鉴定半胱氨酸代谢调控因子（CymR）衍生五肽作为金黄色葡萄球菌O-乙酰-L-丝氨酸巯基酶（CysK）的纳摩尔级抑制剂》，刊载于《ACS Infectious Diseases》2025年第11卷。