WP3300 - Dual hijack model of Vif in HIV infection - Homo sapiens

By hijacking CBF-b, Vif (Viral infectivity factor, HIV protein) is manipulating the ubquitination machinery and adversely effecting host transcriptional regulation. This pathways was adapted from figure 3 in [https://www.ncbi.nlm.nih.gov/pubmed/23352243 Fraser et al]. Viral proteins are highlighted in yellow.