Elemental-Sulfur-Incorporated Cyclizations of Pyrrolidines Leading to Thienopyrroles
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https://figshare.com/articles/dataset/Elemental-Sulfur-Incorporated_Cyclizations_of_Pyrrolidines_Leading_to_Thienopyrroles/12793840
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资源简介：
We report, herein, the synthesis
of thieno[3,2-b]pyrroles from the direct oxidative
[4 + 1] cyclization of 2-alkynyl
pyrrolidines with elemental sulfur. This transformation likely originates
from electrophilic attack at the β-position of pyrrolidine followed
by an intramolecular thienannulation to deliver the desired product.
Mechanistic investigation suggests that the present reaction involves
the formation of dihydrothieno[3,2-b]pyrrole as an
intermediate.
创建时间：
2020-07-23
