Risk of AIDS and/or death according to combinations of clinical and immunological definitions of severe PHI.

a- bronchitis, pneumonia, oral candidiasis, thrombocytopenia, viral meningitis, bacterial meningitis, encephalitis, neuropathy, Candida pharyngitis.b- viral meningitis, bacterial meningitis, encephalitis, neuropathy.*Adjusted for sex, risk group (sex between men, injecting drug use, sex between men and women, other/unknown), age at HIV seroconversion (≤30 and >30 years) and first CD4 count (500 cells/mm3).¤Adjusted for sex, risk group (sex between men, injecting drug use, sex between men and women, other/unknown), age at HIV seroconversion (≤30 and >30 years).¥Long rank test for difference in survivor probabilities.§Cox semiparametric survival model.†Heterogeneity test for categorical variables.‡The symbol “-” for median survival time indicates that fewer than 50% of patients at risk have experienced the event by the end of follow-up.a- 支气管炎、肺炎、口腔念珠菌病、血小板减少症、病毒性脑膜炎、细菌性脑膜炎、脑炎、神经病变、念珠菌性咽炎。 b- 病毒性脑膜炎、细菌性脑膜炎、脑炎、神经病变。 * 校正了性别、风险人群（男男性行为、注射吸毒、男女两性性行为、其他/未知）、HIV血清转换时年龄（≤30岁与＞30岁）以及首次CD4计数（500个细胞/mm³）。 ¤ 校正了性别、风险人群（男男性行为、注射吸毒、男女两性性行为、其他/未知）、HIV血清转换时年龄（≤30岁与＞30岁）。 ¥ 用于比较生存概率差异的log-rank检验（Long rank test）。 § Cox半参数生存模型（Cox semiparametric survival model）。 † 分类变量的异质性检验（Heterogeneity test for categorical variables）。 ‡ 中位生存时间标注为“-”，表示在随访结束时，仅有不足50%的处于风险中的患者发生了研究终点事件。