Common Genetic Variants In Foxp2 Are Not Associated With Individual Differences In Language Development

Three data sets used in” Common Genetic Variants <em>in FOXP2</em> Are Not Associated with Individual Differences in Language Development” are provided. The discovery data set was comprised of 834 children who were members of a Longitudinal sample and children who were members of a School sample. Both samples are contained in the Iowa data set. The Iowa data set contains a quantitative variable LCOMP that represents a composite z-score representing oral language ability. The data set also identifies which sample the children belonged to and the allele calls for 13 tag SNPs located across <em>FOXP2</em>. A second data file, ELVS, contains data from a separate sample of children who were used to test for replication of inconsistent evidence of an association between language and the SNP rs1916988. The ELVS file provides a composite oral language score scaled in standard score units (mean=100, SD=15) and the genotype calls for the SNP rs1916988.本文提供了发表于《FOXP2基因常见遗传变异与语言发育个体差异无关联》（"Common Genetic Variants in FOXP2" Are Not Associated with Individual Differences in Language Development）一文所用的三套数据集。发现数据集共纳入834名儿童，分别来自纵向队列样本与学校队列样本。上述两类队列样本均包含于艾奥瓦数据集（Iowa data set）中。艾奥瓦数据集包含一项名为LCOMP的定量变量，该变量为反映口头语言能力的复合z得分；该数据集同时标注了每名儿童所属的队列样本类型，以及分布于FOXP2基因的13个标签单核苷酸多态性（tag SNPs）的等位基因分型结果。第二个数据文件ELVS包含另一独立儿童队列的数据，该队列用于对语言与SNP rs1916988之间关联的不一致性证据进行重复验证；ELVS文件提供了以标准分（均值=100，标准差=15）表示的复合口头语言得分，以及SNP rs1916988的基因型分型结果。