Online Supplementary materials

<b>Title:</b> Genetically predicted lifelong circulating 25(OH)D levels are associated with serum calcium levels and kidney stone risk. <b>Running head: </b>vitamin D, calcium and kidney stone<b></b> <b>Authors: </b>Zhongyu Jian^a,b, Yu Huang^c, Yazhou He^d, Xi Jin^a, Hong Li^a, Sheyu Li^e,f,g*, Kunjie Wang^a,*. <b>Affiliations: </b> <b>^a</b>Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, People's Republic of China. ^bWest China Biomedical Big Data Center, Sichuan University, Chengdu, People's Republic of China. ^cGuangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. ^dWest China School of Public Health and West China Fourth Hospital, Sichuan University, China. ^eDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China. ^fChinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, West China Hospital, Sichuan University, Chengdu, China. ^gEngineering Research Center of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, Chengdu, China. <b>*Corresponding author: </b>Kunjie Wang; Mailing address: Department of Urology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu City, Sichuan Province, PR China. Telephone number: [phone]. E-mail address: [e-mail]. Sheyu Li; Mailing address: Department of Endocrinology and Metabolism, Chinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, Engineering Research Center of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu City, Sichuan Province, PR China. E-mail address: [e-mail]. <b>Keywords: </b>Mendelian randomization; kidney stone disease; nephrolithiasis; vitamin D.<b></b>

<b>Title:</b> 遗传预测的终身循环25-羟维生素D（25(OH)D）水平与血清钙水平及肾结石风险相关 <b>Running head: </b>维生素D、钙与肾结石<b></b> <b>Authors: </b>简中宇^a,b、黄瑜^c、何亚州^d、金曦^a、李宏^a、李舍予^e,f,g*、王坤杰^a,*. <b>Affiliations: </b> <b>^a</b>泌尿外科、泌尿外科研究所（重建泌尿外科实验室），四川大学华西医院，中华人民共和国四川省成都市。 ^b华西生物医学大数据中心，四川大学，中华人民共和国四川省成都市。 ^c广东省眼科研究所、眼科，广东省人民医院（广东省医学科学院），中华人民共和国广东省广州市。 ^d华西公共卫生学院、华西第四医院，四川大学，中华人民共和国。 ^e内分泌与代谢病科，四川大学华西医院，中华人民共和国四川省成都市。 ^f中国循证医学中心、Cochrane中国中心及MAGIC中国中心，四川大学华西医院，中华人民共和国四川省成都市。 ^g教育部医学信息技术工程研究中心，四川大学华西医院，中华人民共和国四川省成都市。 <b>*Corresponding author: </b>王坤杰；通讯地址：中华人民共和国四川省成都市武侯区国学巷37号四川大学华西医院泌尿外科，电话号码：[phone]，电子邮箱：[e-mail]。李舍予；通讯地址：中华人民共和国四川省成都市武侯区国学巷37号四川大学华西医院内分泌与代谢病科、中国循证医学中心、Cochrane中国中心及MAGIC中国中心、教育部医学信息技术工程研究中心，电子邮箱：[e-mail]。 <b>Keywords: </b>孟德尔随机化（Mendelian randomization）；肾结石病；肾石症；维生素D.<b></b>