Nefecon_IgAN_Clinical_Biomarker_Data_v1.0

This dataset supports the findings from the study: "Real-World Study of Nefecon in the Treatment of IgA Nephropathy: Clinical Efficacy, Biomarkers, and Microbiome Analysis". It contains anonymized clinical data and experimental biomarker results from patients with IgA Nephropathy treated with Nefecon. The dataset includes three file types: 1. Clinical_Data.xls: Anonymized patient demographics, [list other key variables e.g., lab results, treatment response]. 2. ELISA_Concentrations_total.xls: Final calculated concentrations (in pg/mL or as appropriate) for all measured biomarkers, including [list key biomarkers, e.g., Gd-IgA1, BAFF, APRIL] at different time points. 3. Raw_OD_Files: A collection of Excel files containing raw optical density (OD) readings for standard curves and all samples. The naming convention is [Marker]_[Specimen]_[Plate#]_raw_OD.xls. These files allow for independent re-analysis of the standard curves.本数据集用于支撑下述研究的结论：《Nefecon治疗IgA肾病（IgA Nephropathy）的真实世界研究：临床疗效、生物标志物与微生物组分析》。 本数据集包含接受Nefecon治疗的IgA肾病患者的匿名化临床数据与实验生物标志物检测结果。本数据集涵盖三类文件： 1. Clinical_Data.xls：包含匿名化的患者人口统计学信息及其他关键变量（如实验室检测结果、治疗应答指标等）。 2. ELISA_Concentrations_total.xls：包含所有被测生物标志物的最终计算浓度（单位为pg/mL或相应适配单位），涵盖不同时间点的关键生物标志物，例如Gd-IgA1、BAFF、APRIL等。 3. Raw_OD_Files：包含标准曲线与所有样本原始光密度（Optical Density，OD）读数的Excel文件集合，命名规则为[Marker]_[Specimen]_[Plate#]_raw_OD.xls。此类文件可用于对标准曲线开展独立重分析。