Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants

To elucidate the key interrelationships between antigen-adjuvant interactions, storage stability, and in vivo performance to enable successful formulation development of stable and efficacious subunit vaccines.

本研究旨在阐明抗原-佐剂相互作用、储存稳定性与体内性能三者间的核心关联，以助力稳定且高效的亚单位疫苗（subunit vaccines）的成功制剂开发。