Model predictions for the different combinatorial configurations for BCL11B production after the selection based on the 95% confidence interval (CI) and plausible values for the half-lives.

For each of the 8 interaction variants, Eqs 3-10 (S1 File), all combinations of the Hill coefficients of TCF-1 and GATA-3 (i.e. nT,B and nG,B) were considered: (M,M); (M,D); (D,M); and (D,D) where M denotes monomer (Hill coefficient equals to 1) and D for dimer (Hill coefficient equals to 2). Notation: × indicates failure and ✓ success with regard to the CI 95% selection and ✓! those configurations that also give rise to reasonable values for the half-lives.