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Glucocorticoids delay RAF-induced senescence promoted by EGR1

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134747
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资源简介:
Analysis of the transcriptional response to treatment with glucocorticoids in human fibroblasts entering oncogene-induced senescence. BJ-hTert-B-RAF-V600E human cells treated for 24-120 hours with doxycycline to induce B-Raf-V600E expression were treated with clobetasol or compound A for 2 hours before harvest or during the entire time with doxycycline. At least three replicates per sample. Differential expression with clobetasol assessed against control with DMSO (vehicle).
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2019-08-29
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