Genome-wide analysis of microRNA expression in Non-small Cell Lung Cancer

Analysis of NSCLC development at microRNA expression level. Results shows that has-miR-96 is significant up-regulated in the cancer tissue compared with the adjacent normal tissue. Illumina Human v2 MicroRNA expression beadchip Total microRNA obtained from 6 paired NSCLC cancer tissue and the adjacent normal tissue.本研究针对非小细胞肺癌（Non-Small Cell Lung Cancer, NSCLC）的发生发展，开展基于微小RNA（microRNA）表达水平的分析。研究结果表明，相较于癌旁正常组织，人微小RNA-96（has-miR-96）在癌组织中呈显著上调表达。本次检测采用伊卢米纳（Illumina）人类v2版微小RNA表达微珠芯片（Illumina Human v2 MicroRNA expression beadchip），所用总微小RNA样本提取自6对非小细胞肺癌癌组织及其配对癌旁正常组织。