1000 Genomes phase 3, phased and annotated data for use in plink2.0 worked examples

Lightly processed 1000 Genomes phase 3 dataset, directly derived from http://ftp.1000genomes.ebi.ac.uk/vol1/ftp/release/20130502/ . We have corrected a few errors in the official pedigree using the method described in Manichaikul A, Mychaleckyj JC, Rich SS, Daly K, Sale M, Chen WM (2010) Robust relationship inference in genome-wide association studies, however the most notable property of these data are their size: they are ~78% smaller without throwing away any relevant information. This has been achieved by using the latest pre-release version of PLINK (plink2), which can now act as a new form of genomic compression technology. The manuscript describing the new PLINK release is currently in preparation, these data are being made available pre-publication due to demand. <br>Please refer to the 1000 Genomes website for additional sample information, data usage rules,, and citation instructions. <br>

本数据集为经过轻度处理的千人基因组计划（1000 Genomes）第三阶段数据集，直接源自官方源地址：http://ftp.1000genomes.ebi.ac.uk/vol1/ftp/release/20130502/。我们采用Manichaikul A、Mychaleckyj JC、Rich SS、Daly K、Sale M、Chen WM于2010年发表的《全基因组关联研究中的稳健亲缘关系推断》一文中提出的方法，修正了官方家系文件中的若干错误。本数据集最显著的特性在于其体量：在不丢弃任何有效信息的前提下，数据量缩减了约78%。该压缩效果通过使用最新预发布版本的PLINK（plink2）实现，该工具现已可作为一种新型基因组压缩技术。描述新版PLINK的研究论文目前正在撰写中，鉴于用户需求，本数据集于正式出版前先行开放获取。
如需获取更多样本信息、数据使用规范及引用说明，请参阅千人基因组计划官方网站。