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Age, bodyweight, and mesenteric artery dimensions and vascular reactivity for 12 month old wild-type (<i>Rln</i><sup>+/+</sup>) and relaxin-deficient (<i>Rln</i><sup>−/−</sup>) mice.

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NIAID Data Ecosystem2026-03-09 收录
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Baseline (at 5 mmHg) artery dimensions: outer diameter (OD), inner diameter (ID) and wall thickness (WT). Vascular reactivity data: phenylephrine (PE); acetylcholine (ACh); 100 mM potassium PSS (Hi K); nitric oxide synthase inhibitor (L-NAME); indomethacin (Indo); 1-[(2-chlorophenyl) (diphenyl) methyl]-1H-pyrazole and apamin (T34 & Apa); maximum response (Emax); maximum relaxation (Rmax); pD2 sensitivity (−log EC50); N/D not determined. All values are expressed as mean ± SEM and N refers to the sample size. * significantly (P<0.05) greater than Rln+/+ mice. Age, bodyweight, and mesenteric artery dimensions and vascular reactivity for 12 month old wild-type (Rln+/+) and relaxin-deficient (Rln−/−) mice.

5mmHg基线状态下的动脉形态参数:外径(outer diameter, OD)、内径(inner diameter, ID)及管壁厚度(wall thickness, WT)。血管反应性相关检测数据包括:去氧肾上腺素(phenylephrine, PE)、乙酰胆碱(acetylcholine, ACh)、100mM钾离子PSS溶液(Hi K)、一氧化氮合酶抑制剂(nitric oxide synthase inhibitor, L-NAME)、吲哚美辛(indomethacin, Indo)、1-[(2-氯苯基)(二苯基)甲基]-1H-吡唑(T34)与蜂毒明肽(apamin, Apa);最大收缩反应(maximum response, Emax)、最大舒张反应(maximum relaxation, Rmax)、pD2敏感性(−log EC50);N/D代表未测定。所有数据均以平均值±标准误(standard error of the mean, SEM)表示,其中N为样本量;标记*表示该数值较Rln+/+小鼠显著升高(P<0.05)。本数据集涵盖12月龄野生型(wild-type, Rln+/+)及松弛素缺陷型(relaxin-deficient, Rln−/−)小鼠的年龄、体质量、肠系膜动脉形态参数及血管反应性数据。

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2014-09-22
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