Structure of Modified adeno-associated viral vector, AAV5-BCD

NIAID Data Ecosystem2026-05-02 收录

基因治疗载体

AAV载体工程

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Structure of Modified adeno-associated viral vector, AAV5-BCD

改造型腺相关病毒载体（adeno-associated viral vector）AAV5-BCD的结构

创建时间：

2025-04-30

AAV8 human HEK293-produced, empty capsid

腺相关病毒载体

基因治疗载体

AAV8 human HEK293-produced, empty capsid Descriptor: Capsid protein Authors: Paulk, N.K, Poweleit, N. Deposit date: 2019-08-18 Release date: 2020-06-03 Last modified: 2024-03-20 Method: ELECTRON MICRO

Protein Data Bank Japan2024-03-20 更新40

Fab1-4 in complex with the capsid of Adeno-associated virus type 9

病毒衣壳-抗体复合物结构

基因治疗载体

Fab1-4 in complex with the capsid of Adeno-associated virus type 9 Descriptor: Capsid protein VP1, Fab1-4 heavy chain, Fab1-4 light chain Authors: Mietzsch, M, McKenna, R. Deposit date: 2024-03-25 Rel

Protein Data Bank Japan2025-06-11 更新20

Primer design for site-directed mutagenesis of AAV2/2[QuadYF+TV]-based rep-cap plasmids.

AAV载体工程

定点诱变引物设计

Primer design for site-directed mutagenesis of AAV2/2[QuadYF+TV]-based rep-cap plasmids.

NIAID Data Ecosystem10

A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.

病毒复制调控

基因治疗载体

Human cytomegalovirus (CMV) replication begins with the expression of two regulatory proteins, IE1(491aa) and IE2(579aa), produced from differentially spliced transcripts under control of the ie1/ie2

PubMed Central1996-10-15 更新30

A custom-made AAV1 variant (AAV1-T593K) enables efficient transduction of Japanese quail neurons in vitro and in vivo

AAV载体工程

鹌鹑神经科学

The widespread use of rodents in neuroscience has prompted the development of optimized viral variants for transduction of brain cells, in vivo. However, many of the viruses developed are less efficie

NIAID Data Ecosystem20

Structure of Modified adeno-associated viral vector, AAV5-BCD

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