miRRN_MEN1_GEP_NT

"MicroRNAs Regulatory Network governing the epigenetic landscape of MEN1 gastroenteropancreatic neuroendocrine tumour: a case report."

SUPPLEMENTARY DATA TABLES

Table 1: Raw_miRNA_counts.xls
Table containing all the raw mature miRNA counts (according to miRBase 22.1) of the samples used in the current study.

Table 2: Tumour_vs_Ctrl.xls
Table containing the output results of differential expression analysis performed with DESeq2 by comparing tumour (gastrinomas+pNETs) and control MEN1 pancreas. Referred to Figure 4.

Table 3: Gas_vs_Ctrl.xls
Table containing the output results of differential expression analysis performed with DESeq2 by comparing gastrinomas and control MEN1 pancreas. Referred to Figure S1.

Table 4: pNET_vs_Ctrl.xls
Table containing the output results of differential expression analysis performed with DESeq2 by comparing pNETs and control MEN1 pancreas. Referred to Figure S2.

Table 5: miRWalk_GSEA_results.xls
Table containing the results of GSEA (Gene Set Enrichment Analysis) performed on the predicted targets of miRNA regulatory network hubs by miRWalk 3.0.

调控MEN1型胃肠胰神经内分泌肿瘤表观遗传谱的微小RNA（miRNA）调控网络：一则病例报告。

补充数据表格

表1：Raw_miRNA_counts.xls：包含本研究所用样本的全部原始成熟微小RNA计数结果（依据miRBase 22.1数据库）。

表2：Tumour_vs_Ctrl.xls：包含通过DESeq2对肿瘤（胃泌素瘤+胰腺神经内分泌肿瘤（pancreatic neuroendocrine tumours, pNETs））与MEN1型正常胰腺对照进行差异表达分析得到的结果，对应图4。

表3：Gas_vs_Ctrl.xls：包含通过DESeq2对胃泌素瘤与MEN1型正常胰腺对照进行差异表达分析得到的结果，对应补充图S1。

表4：pNET_vs_Ctrl.xls：包含通过DESeq2对胰腺神经内分泌肿瘤（pancreatic neuroendocrine tumours, pNETs）与MEN1型正常胰腺对照进行差异表达分析得到的结果，对应补充图S2。

表5：miRWalk_GSEA_results.xls：包含通过miRWalk 3.0对微小RNA调控网络核心枢纽的预测靶基因进行基因集富集分析（Gene Set Enrichment Analysis, GSEA）得到的结果。