[Evaluation of myocardial deformation by the ecocardiography feature tracking in cats with perimembranosous defect of the septo ventricular]

ABSTRACT The development of new tools, such as two-dimensional feature tracking (2D-FTI), allows early diagnosis of myocardial dysfunction in heart diseases including congenital heart disease. The ventricular septal defect (VSD) is the most frequently observed congenital abnormality in cats, however, little is known about cardiac dysfunction, especially in asymptomatic animals. The objective of this study was to evaluate the left ventricular myocardial deformation through 2D-FTI by the measurement of the radial, circumferential and longitudinal echocardiographic strain (St) and strain rate (StR) indices. Twelve healthy cats and six cats with VSD were evaluated to obtain St and StR in several myocardial segments. In the longitudinal direction, there was a statistical difference (P摘要：新型检测工具的发展，例如二维特征追踪（two-dimensional feature tracking, 2D-FTI），可实现包括先天性心脏病在内的各类心脏疾病心肌功能障碍的早期诊断。室间隔缺损（ventricular septal defect, VSD）是猫类最常见的先天性心脏异常，但目前针对其相关心脏功能障碍的研究尚少，尤其是无症状患病动物。本研究旨在通过2D-FTI技术，测量径向、周向及纵向超声心动图应变（St）与应变率（StR）指标，以评估左心室心肌形变。本研究共纳入12只健康家猫及6只VSD患病家猫，对其多个心肌节段的St与StR指标进行采集分析。在纵向方向上，存在统计学差异（P