Table 3_Online training program maintains motor functions and quality of life in patients with Parkinson's disease.pdf

ObjectiveSeveral systematic reviews have shown that physical exercise positively affects motor function (MF) and quality of life (QoL) in patients with Parkinson's disease (PD). After the coronavirus disease (COVID-19) pandemic, numerous studies were conducted to reveal the effects of telerehabilitation for patients with PD. However, only a few empirical results of online programs for PD patients have been reported. Therefore, this study aimed to determine the effects of an online physical and cognitive training program on MF and QoL in patients with PD.
MethodsWe evaluated the impact of our online program on the QoL and MF of patients with PD by comparing data at baseline and after six months of intervention. For the QoL assessment, we used the Schwab and England Activities of Daily Living scale and Parkinson's Disease Questionnaire (PDQ-39), whereas, for MF, we measured movement status using the modified 20-m walk test and timed up-and-go (TUG) test.
ResultsWe enrolled 20 patients for QoL and 19 for MF in this study. For PDQ-39, social support (p = 0.046, δ = 0.320) and cognitions (p = 0.028, δ = 0.268) significantly improved. Additionally, cadence (p = 0.032, g = −0.377) in the modified 20-m walk and exam duration (p = 0.003, δ = 0.296) and forward gait (p = 0.003, δ = 0.341) in the TUG test showed significant differences before and after the intervention.
ConclusionOur results suggest that online physical and cognitive training programs positively affect MF and QoL in individuals with PD.

研究目的：多项系统综述已证实，体育运动对帕金森病（PD）患者的运动功能（MF）与生活质量（QoL）具有积极影响。新型冠状病毒肺炎（COVID-19）疫情暴发后，学界开展了大量研究以探究远程康复对PD患者的作用效果，但目前针对PD患者的线上干预项目的实证研究结果仍较为匮乏。因此，本研究旨在明确线上躯体与认知训练方案对PD患者运动功能（MF）及生活质量（QoL）的影响。
研究方法：本研究通过对比帕金森病患者干预前基线数据与6个月干预后的随访数据，评估本研究线上项目对其生活质量与运动功能的影响。生活质量评估采用Schwab与England日常生活活动能力量表以及帕金森病生活质量问卷（PDQ-39）；运动功能评估则通过改良20米步行测试与计时起立行走（TUG）测试来量化患者的运动状态。
研究结果：本研究共纳入20例患者用于生活质量分析，19例患者用于运动功能分析。在PDQ-39维度中，社会支持维度（p=0.046, δ=0.320）与认知维度（p=0.028, δ=0.268）得到显著改善。此外，改良20米步行测试的步频（p=0.032, g=-0.377）、TUG测试的测试时长（p=0.003, δ=0.296）以及向前步态（p=0.003, δ=0.341）在干预前后均存在显著差异。
研究结论：本研究结果表明，线上躯体与认知训练方案可对PD患者的运动功能与生活质量产生积极影响。