Distribution of EC50 and slope (γ) values for concentration-effect curves of chloroquine, mefloquine, lumefantrine and artesunate, derived from the two statistical modelling approaches: standard two-stage method and nonlinear mixed-effects modelling.

STS – standard two-stage method; NLME – nonlinear mixed-effects modelling; SD – standard deviation for between-isolate variability.†Geometric mean.‡Calculated from estimated mean & SD (loge scale) and converted to original scale.*95% prediction interval.STS——标准两阶段法（standard two-stage method）；NLME——非线性混合效应模型（nonlinear mixed-effects modelling）；SD——分离株间变异的标准差（standard deviation for between-isolate variability）。†几何均值（Geometric mean）。‡由估算均值与自然对数刻度下的标准差计算得出，并转换至原始尺度。*95%预测区间（95% prediction interval）。