CIL:120, Gallus gallus gallus, erythrocyte. In Cell Image Library

Telomeres isolated from chicken erythrocyte nuclei following restriction endonuclease treatment, and imaged by transmission EM after uranyl acetate negative staining.
Image recorded with FEI Tecnai 12 TEM at 100KV and recorded on 2048x2048 CCD with 2x binning.
Telomeres have a looped conformation, which likely aids in their protection from the rapid degradation that occurs with free DNA ends.

经限制性内切酶处理后，从鸡红细胞核中分离得到的端粒，经醋酸铀负染色后通过透射电子显微镜（transmission EM）成像。本次成像使用FEI Tecnai 12型透射电子显微镜，加速电压设定为100千伏，图像采集于2048×2048像素的电荷耦合器件（CCD），并采用2倍像素合并模式。端粒呈环状构象，该结构或有助于保护端粒免受游离DNA末端易发生的快速降解。