Gene expression profiling in HCV associated liver disease. Homo sapiens

Expression of human genes was compared in liver fibrosis stage F1, F2, F3, and F4 to find markers that can differentiate among each fibrosis stages and cirrhosis. Overall design: Four- condition experiment, F1 vs. F2 vs. F3 vs. F4. Biological replicates: 3 Normal, 3 F1, 3 F2, 3 F3 and 3 F4 stage samples.

本研究比较了肝纤维化分期F1、F2、F3及F4阶段的人类基因表达水平，旨在筛选可区分各纤维化分期与肝硬化的分子标志物。实验设计概述：该实验为四组条件比对实验，即对F1、F2、F3与F4分期样本开展多组比对分析。生物学重复设置：正常样本、F1、F2、F3及F4分期样本各设置3次生物学重复。