Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer

We perform RNA-seq on matched orthotopic murine primary and metastatic prostate cancer samples to identify differential gene expressions RNA-seq was performed on orthotopic murine primary and metastatic tumor samples using Illumina Hi-Seq 2000 platform

我们对配对的原位小鼠原发性及转移性前列腺癌样本开展RNA测序（RNA-seq）以鉴定差异基因表达；本次实验采用Illumina Hi-Seq 2000平台，对原位小鼠原发性肿瘤与转移性肿瘤样本完成RNA测序。