Aortic thrombosis in a dog with chronic lymphocytic leukemia

ABSTRACT: The aim of this report was to describe a case of aortic thrombosis (AT) secondary to chronic lymphocytic leukemia (CLL). Although, different types of neoplasms are described as possible causes of aortic thrombosis, CLL was not yet considered. The dog showed signs of lameness that worsened with exercise. The diagnosis of AT was made by ultrasound examination. The diagnosis of CLL was made by necropsy, which showed the presence of small lymphocytes with the appearance of mature lymphocytes in the bone marrow, spleen, liver and kidneys. The importance of including CLL in the possible causes of AT in dogs, in addition to the suspicion of AT in cases of neuromuscular disease, was highlighted.摘要：本报告旨在描述1例继发于慢性淋巴细胞白血病（chronic lymphocytic leukemia, CLL）的主动脉血栓形成（aortic thrombosis, AT）病例。尽管已有多种肿瘤被报道为主动脉血栓形成的潜在致病原因，但慢性淋巴细胞白血病此前尚未被纳入此类病因范畴。该患犬表现出随运动加重的跛行症状。通过超声检查确诊主动脉血栓形成，经尸检确诊慢性淋巴细胞白血病，尸检结果显示骨髓、脾脏、肝脏及肾脏内存在形态类似成熟淋巴细胞的小淋巴细胞。本研究强调，需将慢性淋巴细胞白血病纳入犬主动脉血栓形成的潜在病因范畴，同时对于表现为神经肌肉疾病的病例，亦应警惕主动脉血栓形成的可能。