Figures and Raw Data for the Manuscript 'LONP1 Regulates Mitochondrial and Microtubule Dynamics to Promote Chlamydial Homotypic Inclusion Fusion'

This study aims to explore how Chlamydia trachomatis regulates mitochondrial and microtubule dynamics through the LONP1 protein, ultimately promoting homotypic inclusion fusion. A range of techniques, including Western blot (WB), immunofluorescence staining, PCR, electron microscopy, and calcium ion live-cell probes, were employed to systematically analyze the role of LONP1 in modulating cellular structure and function during Chlamydia trachomatis infection.本研究旨在探究沙眼衣原体（Chlamydia trachomatis）如何通过LONP1蛋白调控线粒体与微管动力学，最终促进同型包涵体融合。本研究采用免疫印迹（Western blot，WB）、免疫荧光染色、聚合酶链式反应（PCR）、电子显微镜及钙离子活细胞探针等多种技术手段，系统分析了沙眼衣原体感染过程中LONP1在调控细胞结构与功能中的作用。