Nonkeratinizing Carcinoma Tissues: Tumor vs. Adjacent non-tumor tissues. Homo sapiens

Nasopharyngeal carcinoma (NPC) is one of the common malignant tumors, accounting for first place in head and neck malignant tumors. Nonkeratinizing carcinoma (NKC) is the major histologic type of NPC. We performed Transcriptional profiling of NKC comparing tumor with adjacent non-tumor tissues using. Goal was to identify and investigate dryregulated lncRNAs and mRNA in NKC at genome-wide scale. Overall design: Two-paired experiment, Tumor vs. Adjacent Non-tumor Tissues. Biological replicates: 7 paired samples.鼻咽癌（Nasopharyngeal carcinoma, NPC）是常见恶性肿瘤之一，在头颈部恶性肿瘤中位居首位。非角化型癌（Nonkeratinizing carcinoma, NKC）是鼻咽癌的主要组织学类型。本研究采用转录组谱分析（Transcriptional profiling）对比非角化型鼻咽癌组织与邻近非肿瘤组织的转录组表达差异，旨在全基因组范围内鉴定并探究非角化型鼻咽癌中异常调控的长链非编码RNA（long non-coding RNA, lncRNA）与信使RNA（messenger RNA, mRNA）。总体实验设计：采用双配对实验方案，即肿瘤组织与邻近非肿瘤组织对照；生物学重复设置为7对配对样本。