Comparison of the Most Common Taxa Between the Tacrolimus Groups.

At each of the most common taxa at the phylum, order, genus, and species levels, the mean bacterial abundances in the post-transplantation week 1 fecal specimens from the 5 transplant recipients in the Dose Escalation Group were compared to the mean bacterial abundances in those from the 14 transplant recipients in the Dose Stable Group. Unadjusted p values were calculated using Wilcoxon rank sum tests and the adjusted p values were calculated using the Benjamini-Hochberg correction for multiple hypotheses at each taxonomic level. Fecal Faecalibacterium prausnitzii abundance at week 1 post-transplantation was significantly higher in the Dose Escalation Group than in the Dose Stable Group (mean 11.8% vs. 0.8%, respectively, uncorrected P = 0.002, Wilcoxon rank sum test, P<0.05 after Benjamini-Hochberg correction for multiple hypotheses).
Comparison of the Most Common Taxa Between the Tacrolimus Groups.