Design, surgical and ophthalmoscopic observations.

Cells with italicized font are excluded from the quantitative post mortem analysis shown in Fig. 1 due to injection issues as highlighted in the notes column; % SR and IV reflect estimates of vector deposit in subretinal and vitreal spaces respectively; GFP Score ranges from 0 (no visible expression) to 4 (broad and intense GFP) and reflects a subjective composite of both intensity and area of transduction as observed by indirect ophthalmoscopy; F: foveal; B: blood; A: visible air bubble; 2x: injection procedure was interrupted following sclerotomy and restarted making use of the initial sclerotomy a second time due to technical concerns; SRPE: subRPE or choroidal injection; JFL: juxtafoveal; M: macular hole; SR: subretinal; IV: intravitreal; ID: identification number; GFP: green fluorescent protein; OD: optic disc.因注射操作问题（详见备注栏标注），带有斜体字体的细胞被排除在图1所示的定量死后分析之外；其中% SR与% IV分别代表载体在视网膜下（subretinal）间隙与玻璃体内（intravitreal）的沉积量估算值；GFP评分（green fluorescent protein，绿色荧光蛋白）的取值范围为0（无可见表达）至4（广泛且强烈的绿色荧光蛋白表达），该评分基于间接检眼镜观察到的转导强度与转导面积的主观综合评价；F：黄斑中心凹（foveal）；B：血液（blood）；A：可见气泡（visible air bubble）；2x：注药操作于巩膜切开术后因技术顾虑中断，随后第二次使用初始巩膜切口重启注药流程；SRPE：视网膜色素上皮下（subRPE）或脉络膜内注射；JFL：黄斑中心凹旁（juxtafoveal）；M：黄斑裂孔（macular hole）；SR：视网膜下（subretinal）；IV：玻璃体内（intravitreal）；ID：识别编号（identification number）；GFP：绿色荧光蛋白（green fluorescent protein）；OD：视盘（optic disc）。