Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision

Original, uncropped raw data files of EMSA, dot blots and western blots associated with the study: "Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision". The study identifies pre-mRNA to be the main target of immunoregulatory RNA-binding protein tristetraprolin (TTP), which by its nuclear RNA targeting strategy regulates the fidelity of inflammatory responses. The lead contact will share the raw confocal imaging data reported here upon request.本数据集关联研究《胞质mRNA降解调控炎症基因表达由前mRNA (pre-mRNA) 命运决定》的电泳迁移率变动分析 (EMSA)、斑点印迹 (dot blots) 与蛋白质印迹 (western blots) 未裁剪原始数据文件。该研究证实前mRNA (pre-mRNA) 是免疫调节性RNA结合蛋白三联丝氨酸蛋白 (tristetraprolin, TTP) 的主要靶标，该蛋白通过其核RNA靶向策略调控炎症应答的保真度。本研究的通讯作者可应请求提供本文报道的共聚焦成像原始数据。