Culture-based screening and whole-genome sequencing of commensal bacteria from healthy human feces

This project isolated four commensal bacterial strains (Bacteroidetes, Actinobacteria, Firmicutes, and Proteobacteria) from healthy human feces using culturomics approaches. Through whole-genome sequencing and subsequent analysis, we aim to investigate strain-specific interaction mechanisms under various gut environmental conditions, providing a theoretical foundation for probiotic development and gut microbiome research.