Additional file 2 of Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells

Additional file 1: Figure S1. Oncogenic Akt1myr alone does not induce stromal changes and increased immune cell infiltration with cerulein injections. Table S1. Akt1Myr/KRasG12D mice with chronic inflammation progresses to more severe pancreatic cancer and metastasis compared to KRasG12D mice. Figure S2. Immune cell infiltration in pancreatic cancer. Figure S3. Gating strategy for identification of M1 and M2 macrophage populations. Figure S4. Gating strategy for identification of cytotoxic and non-cytotoxic eosinophil populations. Table S2. Patient information and pathology for tissue samples evaluated for IL-5Rα.

补充文件1：图S1。单独的致癌型Akt1myr无法经雨蛙素（cerulein）注射诱导基质改变与免疫细胞浸润增多。表S1。与KRasG12D小鼠相比，携带慢性炎症的Akt1Myr/KRasG12D小鼠会进展为更严重的胰腺癌并发生转移。图S2。胰腺癌组织中的免疫细胞浸润情况。图S3。M1与M2型巨噬细胞群体的鉴定门控策略。图S4。细胞毒性与非细胞毒性嗜酸性粒细胞群体的鉴定门控策略。表S2。针对白细胞介素-5受体α亚基（IL-5Rα）进行评估的组织样本的患者信息与病理学资料。